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 | What is Whooping Cough? |
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Wilson's disease is a hereditary disorder that causes too much copper to accumulate in your liver, brain and other vital organs. This potentially fatal disease shows up in a variety of different ways, but can remain silent for years.
Bile is the brown liquid produced by your liver to aid in digestion. Bile normally carries away excess copper from your liver. The liver of someone with Wilson's disease doesn't release copper into the bile as it should. The resulting buildup of copper in the liver causes injury to the tissue. Eventually, some of the excess copper travels throughout the body, where it may damage your brain, eyes, kidneys and red blood cells.
Left untreated, the liver damage can lead to cirrhosis, an irreversible scarring of the liver that seriously disrupts its normal functioning.
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| Causes of Wilson's disease |
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An abnormal gene inherited as a recessive trait causes Wilson's disease. This gene controls a protein that transports copper in the liver. For people to exhibit signs and symptoms of the disease, they must inherit two copies of the abnormal gene, one from their mother and one from their father.
Children won't develop signs and symptoms of the disease if they inherit the gene from only one parent. Instead, they become carriers of the disease, meaning they can pass on a copy of the abnormal gene to their offspring.
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| Symptoms of Wilson's disease |
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Symptoms of Wilson's disease usually appear between the ages of 6 and 20, but they can appear as late as age 50. The symptoms of Wilson's disease fall into three main categories:
Liver problems
Wilson's disease can mimic any form of acute or chronic liver disease. Possible signs and symptoms include abdominal pain and yellowing of the skin (jaundice). Sometimes, the liver damage progresses without any obvious symptoms until cirrhosis develops. In the advanced stages of disease, more serious signs and symptoms, such as anemia or the vomiting of blood, can occur.
Neurological problems
The most common neurological signs and symptoms in people with Wilson's disease are tremors and muscle spasticity. Speech problems may also occur.
Behavioral or psychological problems
Wilson's disease can cause abrupt personality changes and inappropriate behavior. Sometimes, signs and symptoms in school-age children, such as depression, erratic behavior or failing school performance, are mistaken for behavioral problems.
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| Complications? |
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While whooping cough is very unpleasant, there may also be other complications, such as bronchitis, pneumonia and ear infections. These complications may cause a high temperature, and change the course of the disease. If one or more of these problems occur, they will usually be treated with antibiotics.
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