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 | Overview |
| | is a degenerative disease of the nervous system associated with trembling of the arms and legs, stiffness and rigidity of the muscles and slowness of movement (bradykinesia). A third of those affected by the disease go on to develop senile dementia. Seriously affected patients may suffer from complications such as pneumonia, septicaemia (blood poisoning), stroke, urinary tract infection and pressure sores and some of these may be fatal. |
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| Causes |
| | It is caused by the progressive loss of (neurones) in a part of the brain called the substantia nigra, which produces the chemical dopamine. As the cells die, less dopamine is produced and transported to the striatum, the area of the brain that co-ordinates movement. Symptoms develop as neurones die off and dopamine levels drop. Research suggests may also lack other brain chemicals including serotonin (linked to mood), noradrenaline (linked to blood pressure control) and acetylcholine (linked to mental state). |
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| Symptoms |
| | The main symptoms ofare: tremor, usually while resting. stiffness and muscle cramps known as rigidity, particularly affecting the arm, leg and neck. slowness in initiating movement known as bradykinesia. poor balance and unstable walking (shuffling, difficulty in turning, falls).
Other symptoms include: |
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| Risk Factors |
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