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Home Disease Index Hepatitis (liver inflammation)

 


Overview

Causes
Symptoms
Risk Factor

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Overview

 

Hepatitis is the Latin word for liver inflammation. It is characterised by the destruction of a number of liver cells and the presence of inflammatory cells in the liver tissue. Hepatitis can be caused by diseases that primarily attack the liver cells. It can also arise as a result of a disease such as mononucleosis. Hepatitis can be divided into two subgroups according to its duration:

  • acute hepatitis - lasting less than six months
  • chronic hepatitis - lasting longer than six months.



Causes

 

What can cause acute hepatitis?

Acute hepatitis has a number of possible causes.

  • Infectious viral hepatitis such as hepatitis A, hepatitis B, hepatitis C, hepatitis D and hepatitis E.
  • Other viral diseases such as: mononucleosis and cytomegalovirus.
  • Severe bacterial infections.
  • Amoebic infections.
  • Medicines, eg paracetamol poisoning and halothane (an anaesthetic).
  • Toxins: alcohol and fungal toxins, eg toadstool poisoning.

What can cause chronic hepatitis?

Chronic hepatitis also has a number of different causes.

  • Contagious viral hepatitis such as hepatitis B, hepatitis C and hepatitis D.
  • Medicines.
  • Toxins such as alcohol.
  • Autoimmune hepatitis. This is a disease in which a number of liver cells are destroyed by the patient's own immune system. Autoimmune hepatitis can also sometimes occur as acute hepatitis. The cause is unknown.
  • Inborn metabolic disorders, such as Wilson's disease (disorder of the body's copper metabolism) and haemochromatosis (disorder of the body's iron metabolism).

 



Symptoms

 

Acute Hepatitis

The symptoms of acute hepatitis vary considerably from person to person. Some patients have no symptoms at all, and in most cases, children only show mild symptoms.

In the early stages:

  • tiredness, general malaise, slight fever
  • nausea, poor appetite, changes in taste perception
  • pressure or pain below the right ribs caused by an enlarged liver
  • aching muscles and joints, headache, skin rash.

The jaundice phase:

  • yellowing of sclerae (the white portions of the eyes), skin and mucous membranes
  • dark urine
  • light-coloured stools
  • around this time, the other symptoms subside.

The recovery phase:

tiredness that can last for weeks.

Chronic Hepatitis

  • Many patients have no symptoms.
  • Tiredness, an increased need for sleep, aching muscles and joints.
  • Periodic light pressure or pain below the right ribs - enlarged liver.
  • Jaundice is a very late symptom of chronic hepatitis. It is a sign that the disease has become serious.

 

Risk Factors

 
  • Patients with jaundice or other symptoms of hepatitis.
  • People who are very likely to have contracted the hepatitis B or the hepatitis C virus.
  • People who are at increased risk due to a hereditary type of hepatitis in their families.

 


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